Oxigene Therapeutics About 
Oxigene OXiGENE is an emerging pharmaceutical company developing 
novel small-molecule therapeutics to treat cancer and eye diseases. The Company’s 
major focus is the clinical advancement of drug candidates that selectively disrupt 
abnormal blood vessels associated with solid tumor progression and visual impairment. 
Oxigene's flagship compound is Combretastatin CA4 Prodrug      Combretastatin CA4 -- Combretastatin 
represents a new class of therapeutic compounds known as vascular targeting agents. 
These agents may be useful in disease conditions or pathologies such as cancer, 
where an abnormal growth of blood vessels is an essential component to the disease 
and its progression. Combretastatin has shown the ability in both preclinical 
animal model and clinical trials to drastically reduce blood flow in tumors.    CA4P 
-- Anaplastic Thyroid Cancer; Imageable Tumors    More 
on Oxigene