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Human Genome Sciences

About Human Genome Sciences

Human Genome Sciences is a biopharmaceutical company with a product pipeline derived primarily from proprietary genomic technology. Their goal is to create a global biopharmaceutical company to discover, develop, manufacture, and market gene-based protein and antibody drugs to treat and cure disease.

Products in clinical development focus on two main therapeutic areas, immunology/infectious disease and oncology.The core pipeline currently includes six products for use in the treatment of systemic lupus, erythematosus, rheumatoid arthritis, chronic hepatitis C, and a variety of cancers such as non-small cell lung cancer, colorectal cancer and non-Hodgkin’s lymphoma.


Pipeline for Human Genome Sciences



LymphoStat-B --specifically recognizes and inhibits the biological activity of B-lymphocyte stimulator, or BLyS™. --for autoimmune diseases e.g., lupus and rheumatoid arthritis

Albuferon -- a novel long-acting form of interferon alpha for the treatment of hepatitis C, hepatitis B, and a broad range of cancers

ABtrax -- Human monoclonal antibody to bacillus anthracis protective antigen

HGS-ETRI -- anti-cancer drug that specifically binds to the TRAIL Receptor-1 protein and triggers programmed cell death, or apoptosis, in cancer cells. HGS-ETR1

HGS-TR2J -- agonistic human monoclonal antibody that specifically binds to the TRAIL Receptor-2 protein -- causing apoptosis (cell death) in tumors.

480848 -- inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) an enzyme associated with the formation of atherosclerotic plaques



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