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ENCYSIVE Pharmaceuticals

About Encysive

Encysive Pharmaceuticals is a pharmaceutical company that discovers, develops and commercializes small molecule drugs aimed at cardiovascular and inflammatory diseases.

Encysive has one of the broadest product pipelines in the sector. With this strong foundation,they are well positioned to become a recognized leader in the discovery, development, and marketing of differentiated drugs that improve survival and quality of life for victims of serious cardiovascular and inflammatory diseases such as: heparin-induced thrombocytopenia (HIT) pulmonary hypertension essential hypertension chronic heart failure multiple sclerosis asthma atherosclerosis


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Argatroban (FDA approved) was developed to treat heparin-induced thrombocytopenia (HIT), a serious immune reaction to heparin that causes abnormal clotting and often leads to limb amputation and even death.

Thelin (sitaxsentan), is an endothelin receptor antagonist being developed as a treatment for pulmonary arterial hypertension (PAH).

BIMOSIAMOSE Clinical trials are now underway (with corporate partners) with Bimosiamose as an inhaled therapy for asthma. Clinical trials are also ongoing with Bimosiamose for treating psoriasis and atopic dermatitis.

TBC3711 Based on the positive data received for sitaxsentan, their first endothelin A antagonist, Encysive believes TBC3711 holds promise as a next generation compound.



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