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Corcept Therapuetics

About Corcept:

Corcept is a pharmaceutical company engaged in the development of drugs for the treatment of severe psychiatric and neurological diseases.Their lead product candidate is CORLUXTM, for the treatment of the psychotic features of psychotic major depression, a disorder that affects approximately three million people in the United States each year and for which there are no FDA-approved treatments. They have also initiated a clinical study to evaluate the tolerability and efficacy of their medicine in improving cognition in patients with mild to moderate Alzheimer's disease.

CORLUX, also known as mifepristone, works by selectively blocking the binding of cortisol, a steroid hormone, to one of its two known receptors. Elevated levels and abnormal release patterns of cortisol have been implicated in a broad range of human disorders, including PMD. By modifying the level and release pattern of cortisol within the human body, Corcept believes that CORLUX will be able to treat the psychotic features of PMD more quickly and effectively and with fewer side effects than is possible with currently available treatments.


Phase IIICorlux ( mifepristone) Psychotic major depression, Alzheimers


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